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Course Unit Code	Course Unit Title	Type of Course Unit	Year of Study	Semester	Number of ECTS Credits
KIMS4815	QUALİTY AND CONTROL İN THE LABORATORY		4	8	4,00

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Lisans

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Language of Instruction

Turkish

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Objectives of the Course

The aim of this course is to provide knowledge and practical competence in laboratory quality control systems, accuracy of analysis, uncertainty, reliability, laboratory accreditation, and standardization in chemical laboratories.

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Name of Lecturer(s)

Assist Prof. Dr. Hatice ARI

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Learning Outcomes

1	Explains laboratory quality management systems.
2	Defines calibration, accuracy, and uncertainty concepts.
3	Applies method validation and control techniques.
4	Evaluates accreditation and auditing processes.
5	Interprets reliability of analytical results.

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Mode of Delivery

Formal Education

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Prerequisities and Co-Requisities

None

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Recommended Optional Programme Components

None

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Content of the Course

Laboratory quality management systems, ISO 17025 standard, internal quality control practices, calibration, measurement uncertainty, accuracy and repeatability, reference materials, method validation, internal and external audit, accreditation procedures.

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Weekly Detailed Course Contents

Week	Subjects (Theoretical)	Teaching Methods	Preparatory
1	Introduction to quality and quality in laboratories	Lecture, concept mapping	Read basic concepts on quality and laboratory management.
2	ISO 17025 standard and its principles	Diagram-based lecture, comparison chart	Review scope and principles of ISO 17025 standard.
3	Internal quality control applications	Practical example analysis	Research sample protocols for internal quality control plans.
4	Calibration procedures and standard curves	Calculation exercise, graph plotting	Practice calibration calculations and standard curve drawing.
5	Concept of measurement uncertainty	Interactive lecture, formula solving	Solve sample calculations on measurement uncertainty.
6	Accuracy and repeatability	Group work, data interpretation	Analyze data on accuracy and repeatability.
7	Reference materials and traceability	Conceptual presentation, case study	Conduct a literature review on reference materials and traceability.
8	Method validation – parameters	Discussion, control chart preparation	Research method validation parameters (e.g. LOQ, LOD).
9	Method validation – practical applications	Protocol writing, experimental application	Write protocols for method validation applications.
10	Internal audit processes and quality documentation	Scenario solving, documentation review	Review quality documents related to internal audit processes.
11	External audit and accreditation	Comparative analysis, regulation review	Study accreditation processes and agencies.
12	Case studies in food, environmental, and biochemical labs	Case study presentation	Examine quality management examples in food and environmental labs.
13	Planning of quality management implementation	Implementation plan development	Design a practical implementation plan for lab quality systems.
14	General review and evaluation	General review, Q&A session	Review all concepts and solve example questions.

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Text Book / Material / Recommended Resources

Skoog, D. A., West, D. M., Holler, F. J., & Crouch, S. R. (2018). Fundamentals of Analytical Chemistry. Cengage Learning. TS EN ISO/IEC 17025:2017 Standard – General Requirements for the Competence of Testing and Calibration Laboratories. Recent publications from TURKAK, TSE and EUROLAB on laboratory quality. Instructor-provided practice documents and technical sector reports.

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Planned Learning Activities and Teaching Methods

None

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Assessment Methods and Criteria

Term (or Year) Learning Activities	Quantity	Weight
Midterm Examination	1	50
Quiz	1	50
Total		100
End Of Term (or Year) Learning Activities	Quantity	Weight
Final Examination	1	100
Total		100
Term (or Year) Learning Activities		40
End Of Term (or Year) Learning Activities		60

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Work Pacement(s)

None

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Workload Calculation

Activities	Number	Time (hours)	Total Work Load (hours)
Midterm Examination	1	1	1
Final Examination	1	1	1
Quiz	1	1	1
Attending Lectures	14	2	28
Self Study	14	3	42
Individual Study for Mid term Examination	3	3	9
Individual Study for Final Examination	4	4	16
Individual Study for Quiz	2	2	4
Total Work Load (hours)			102

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Contribution of Learning Outcomes to Programme Outcomes

	PO 1	PO 2	PO 3	PO 4	PO 5	PO 6	PO 7	PO 8	PO 9	PO 10	PO 11	PO 12	PO 13	PO 14	PO 15
LO 1	2	2										2
LO 2	2	2										2
LO 3	2	2										2
LO 4	2	2										2
LO 5	2	2	3									2