BACK
Description of Individual Course Units
| Course Unit Code | Course Unit Title | Type of Course Unit | Year of Study | Semester | Number of ECTS Credits |
|---|---|---|---|---|---|
| KIMS3502 | PHARMACEUTİCAL CHEMİSTRY | 3 | 5 | 4,00 |
Level of Course Unit
Lisans
Language of Instruction
Turkish
Objectives of the Course
The aim of this course is to give general information about the sources, production techniques and analysis of drugs used from past to present.
Name of Lecturer(s)
Prof. Dr. Mustafa SAÇMACI
Learning Outcomes
| 1 | Have knowledge about the definition of the drug, the chemistry of the drug, the form of the drug and the mechanism of action of the drug. |
| 2 | Learns the biological and chemical properties and structure-activity relationships of drugs. |
| 3 | Gains knowledge about classification, nomenclature of drugs and synthesis of drug active ingredients. |
| 4 | Learns instrumental techniques used in drug analysis. |
| 5 | Have information about the metabolism of the active ingredients of the drug and the ways of metabolism of the drug. |
Mode of Delivery
Formal Education
Prerequisities and Co-Requisities
None
Recommended Optional Programme Components
None
Content of the Course
Introduction to pharmaceutical chemistry and basic concepts. Active drug concept. Classification of drugs. Naming of drugs. Synthesis of drugs. Medication side effects. Receptors and drug-receptor interactions. Structure-activity relationships. Resolution-partition coefficient. Acid-base properties and ionization. Bioisostere. Drug metabolism. Instrumental techniques used in drug analysis. Antibiotics, synthesis and properties of anesthetic compounds. Synthetic analgesic drugs. Drug groups used in treatment: Drugs that affect the peripheral nervous system, drugs that affect the autonomic nervous system, cancer drugs, antiallergics, vitamins. Drug design and new drug development.
Weekly Detailed Course Contents
| Week | Subjects (Theoretical) | Teaching Methods | Preparatory |
|---|---|---|---|
| 1 | Drug definition and sources | Lecture, Discussion, Question and Answer, Brainstorming. | Study from books and Internet resources. |
| 2 | Historical development of drugs | Lecture, Discussion, Question and Answer, Brainstorming. | Study from books and Internet resources. |
| 3 | General information about drugs | Lecture, Discussion, Question and Answer, Brainstorming. | Study from books and Internet resources. |
| 4 | Classification of drugs | Lecture, Discussion, Question and Answer, Brainstorming. | Study from books and Internet resources. |
| 5 | Drug design and new drug development | Lecture, Discussion, Question and Answer, Brainstorming. | Study from books and Internet resources. |
| 6 | Production techniques of drugs | Lecture, Discussion, Question and Answer, Brainstorming. | Study from books and Internet resources. |
| 7 | Gravimetric analyzes of drugs | Lecture, Discussion, Question and Answer, Brainstorming. | Study from books and Internet resources. |
| 8 | Titrimetric analysis of drugs | Lecture, Discussion, Question and Answer, Brainstorming. | Study from books and Internet resources. |
| 9 | Instrumentation analysis of drugs | Lecture, Discussion, Question and Answer, Brainstorming. | Study from books and Internet resources. |
| 10 | Instrumentation analysis of drugs | Lecture, Discussion, Question and Answer, Brainstorming. | Study from books and Internet resources. |
| 11 | Pharmaceutical quality control tests | Lecture, Discussion, Question and Answer, Brainstorming. | Study from books and Internet resources. |
| 12 | Drug safety | Lecture, Discussion, Question and Answer, Brainstorming. | Study from books and Internet resources. |
| 13 | Pharmaceutical industry | Lecture, Discussion, Question and Answer, Brainstorming. | Study from books and Internet resources. |
| 14 | Pharmaceutical industry in Turkey | Lecture, Discussion, Question and Answer, Brainstorming. |
Text Book / Material / Recommended Resources
1) Principles of Organic Medicinal Chemistry, Prof. Dr. Rama Rao Nadendla, New Age International (P) Limited, Publishers, New Delhi, ISBN (13) : 978-81- 224-2485-0, 2005, 331 pp. 2) Farmasötik ve Medisinal Kimya Ders Kitabı, (Yapı Etki İlişkileri), Doç. Dr. Ningur Noyanalpan, Ankara Üniversitesi Eczacılık Fakültesi Yayınları No: 49, Ankara, 1978. 3) A study on cancer and its drugs with their molecular structure and mechanism of action: A Review Priyanka Sonker, Ashish Kumar Tewari, Shail Kumar Chaube , Ranjeet Kumar , Vishal Prasad Sharma , Akhilesh Sonker, Priyanka Yadav, World J Pharm Sci 2018; 6(7): 13-34.
Planned Learning Activities and Teaching Methods
Assessment Methods and Criteria
| Term (or Year) Learning Activities | Quantity | Weight |
|---|---|---|
| Midterm Examination | 1 | 40 |
| Homework | 1 | 60 |
| Total | 100 | |
| End Of Term (or Year) Learning Activities | Quantity | Weight |
| Final Examination | 1 | 100 |
| Total | 100 | |
| Term (or Year) Learning Activities | 40 | |
| End Of Term (or Year) Learning Activities | 60 | |
Work Pacement(s)
None
Workload Calculation
| Activities | Number | Time (hours) | Total Work Load (hours) |
|---|---|---|---|
| Final Examination | 1 | 1 | 1 |
| Quiz | 3 | 1 | 3 |
| Attending Lectures | 14 | 2 | 28 |
| Brain Storming | 14 | 2 | 28 |
| Self Study | 14 | 2 | 28 |
| Individual Study for Final Examination | 1 | 3 | 3 |
| Reading | 3 | 1 | 3 |
| Individual Study for Quiz | 3 | 1 | 3 |
| Homework | 2 | 2 | 4 |
| Total Work Load (hours) | 101 | ||
Contribution of Learning Outcomes to Programme Outcomes
| PO 1 | PO 2 | PO 3 | PO 4 | PO 5 | PO 6 | PO 7 | PO 8 | PO 9 | PO 10 | PO 11 | PO 12 | PO 13 | PO 14 | PO 15 | |
| LO 1 | 5 | 4 | 3 | 3 | 4 | 5 | 5 | 5 | 2 | 2 | 3 | 3 | 3 | 4 | 4 |
| LO 2 | 5 | 4 | 3 | 3 | 4 | 5 | 5 | 5 | 2 | 2 | 3 | 3 | 3 | 4 | 4 |
| LO 3 | 5 | 4 | 3 | 3 | 4 | 5 | 5 | 5 | 2 | 2 | 3 | 3 | 3 | 4 | 4 |
| LO 4 | 5 | 4 | 3 | 3 | 4 | 5 | 5 | 5 | 2 | 2 | 3 | 3 | 3 | 4 | 4 |
| LO 5 | 5 | 4 | 3 | 3 | 4 | 5 | 5 | 5 | 2 | 2 | 3 | 3 | 3 | 4 | 4 |
* Contribution Level: 1 Very low 2 Low 3 Medium 4 High 5 Very High